What additional workup/tests are indicated?

A 56-year-old man presents with a complaint of rash and bleeding from the nose and mouth for the past week. His history is notable for non-Hodgkin lymphoma (NHL;follicular center cell) treated with chemotherapy and radiation therapy I 0 years prior. He has been taking cholesterol lowering medication for 3 years; no new drugs have been prescribed. Examination is notable for a petechial rash, which is prominent on the feet and shins, and multiple blood blisters in the mouth. The remainder of the examination is benign. CBC: Hemoglobin/hematocrit – 12 g/dU36% MCV – 84 fL WBC count – 7,500/tL Platelet count – I 0,000/-tL • SMEAR MORPHOLOGY Normocytic, normochromic; no abnormal red cell morphology. White blood cells are normal. There are very few platelets; giant platelets are noted.

Questions • What abnormality is apparent from the complete blood count (CBC)?

• What additional workup/tests are indicated?

find the cost of your paper

Based on smear morphology and the red blood cell indices (mean cell volume [MCV], mean cell hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC]), the patient has a severe microcytic, hypochromic anemia most likely caused by iron deficiency (see Chapter 5).

Based on smear morphology and the red blood cell indices (mean cell volume [MCV], mean cell hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC]), the patient has a severe microcytic, hypochromic….

Given the diagnosis of HHT, how should this patient be managed?

The patient's history and physical examination (telangiectasia involving the lips, tongue, and palms) are consistent with a diagnosis of hereditary hemorrhagic telangiectasia (HHT). Three diagnostic criteria are met: multiple telangiectases,….

As this patient with HHT grows older, her bleeding tendency will likely become progressively more difficult to manage.

As this patient with HHT grows older, her bleeding tendency will likely become progressively more difficult to manage. If she were premenopausal, oral contraceptives would be an option, but in….